What happens when you combine a red-hot quarterback against the team that gives up the most explosive plays in the league? You lock him into your lineups and play him as he throws for 300 yards and 3 TDs.
QB: Patrick Mahomes, Chiefs
Houston’s run defense is solid, but their pass defense has been a disaster. Mahomes is dealing with a bad ankle, but I still expect him to play well as the Chiefs seek a first-round BYE. Look for Mahomes to have 250 passing yards and 2 TDs.
QB: Baker Mayfield, Bucs
Baker has arguably played at an MVP level and gets the Cowboys, who have been reeling defensively. Vegas has the Bucs scoring four TDs; Baker should throw for three of those.
QB: Kyler Murray, Cardinals
Murray is maddeningly inconsistent, but when given time to throw, he is effective. Carolina struggles to put pressure on the quarterback, so Kyler should have time to find his receivers and put up 225 yards passing with 2 TDs.
QB: Aaron Rodgers, Jets
Rodgers is just padding his stats as he decides on whether to return to the NFL in 2025. The more TDs he throws, the more he can ask for in his next contract. He should throw for 240 yards and another 2 TDs this week to get to 500 TDs in his career.